×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.
12865922 2003
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
High proportion of large genomic STK11 deletions in Peutz-Jeghers syndrome.
16287113 2005
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer.
9887330 1999
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome.
17404884 2007
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Two novel mutations and a new STK11/LKB1 gene isoform in Peutz-Jeghers patients.
12112668 2002
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Mutations in the human LKB1/STK11 gene.
16110486 2005
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation.
19892943 2009
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites.
15608654 2005
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
STK11 genotyping and cancer risk in Peutz-Jeghers syndrome.
15863673 2005
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Nine novel germline mutations of STK11 in ten families with Peutz-Jeghers syndrome.
9760200 1998
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.
9428765 1998
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Genetic defects underlying Peutz-Jeghers syndrome (PJS) and exclusion of the polarity-associated MARK/Par1 gene family as potential PJS candidates.
17924967 2007
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Relative frequency and morphology of cancers in STK11 mutation carriers.
15188174 2004
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome.
10623683 2000
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
16707622 2006
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Novel and recurrent mutations of STK11 gene in six Chinese cases with Peutz-Jeghers syndrome.
24604241 2014
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Mutation analysis of the STK11/LKB1 gene and clinical characteristics of an Australian series of Peutz-Jeghers syndrome patients.
12372054 2002
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.
9850045 1998
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Genotype-phenotype correlations in Peutz-Jeghers syndrome.
15121768 2004
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Clinical characteristics and STK11 gene mutations in Chinese children with Peutz-Jeghers syndrome.
26607058 2015
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer.
9809980 1998
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.
12552571 2003
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase: an X-ray crystallographic study of complexes with various metals and peptide substrate SP20.
23672593 2013
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma.
11389158 2001
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Neoplastic Syndromes, Hereditary
0.120
CausalMutation
CLINVAR
High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.
21118512 2010